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Can you take magnesium and melatonin together?

verdavita editorial team · 2026-11-05

The NIH pages we reviewed do not say whether this combination is safe or useful. Ask your doctor or pharmacist first, especially if you take medication.

What NCCIH says about melatonin

NCCIH says short-term use appears safe for most people, but information on long-term safety is lacking. Reported side effects in short-term studies include headache, dizziness, nausea and sleepiness.

It also says melatonin may stay active longer in older people and cause daytime drowsiness. People taking medicine should check with their health care provider first, and people with epilepsy or taking blood thinners need medical supervision.

What the NIH says about magnesium

The upper limit from supplements and medications is 350 mg a day for adults, unless a health care provider advises otherwise. Magnesium may also interact with some medications.

Read both labels

Check whether a product already contains the other ingredient. Our Deep Sleep lists 2 mg of melatonin, while Calm Night lists 275 mg of magnesium and no melatonin.

Label accuracy is another reason to be careful. NCCIH cites a 2023 study in which 22 of 25 melatonin gummy products were inaccurately labeled.

22 of 25 gummy products were inaccurately labeledMeasured melatonin compared with the label100% = label amount74%347%
Study of 25 over-the-counter gummy products, 2023, as cited by NCCIH. One product had no detectable melatonin.

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Sources

General information, not medical advice. Images are illustrative.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

* Individual results may vary. Reviews reflect the experiences of individual customers.

Consult your healthcare provider before starting any supplement, especially if you are pregnant, nursing, taking medication or have a medical condition.